TY - JOUR AU - Debnath, Sanjit AU - Hore, Samrat AU - Das, Panna AU - Saha, Ajay Krishna PY - 2022/10/05 Y2 - 2024/03/28 TI - THE EVALUATION OF SELECTED BIOACTIVITIES OF FUNGAL MYCELIUM OF A WILD Schizophyllum commune Fr. FROM SUBMERGED CULTURES JF - Journal of microbiology, biotechnology and food sciences JA - J microb biotech food sci VL - 12 IS - 2 SE - Microbiology DO - 10.55251/jmbfs.3250 UR - https://office2.jmbfs.org/index.php/JMBFS/article/view/3250 SP - e3250 AB - <p><em>Schizophyllum commune</em> is a widely distributed macrofungal species assorted with bioactivities. The specific objectives were evaluation of antibacterial and antioxidant properties, synthesis of exopolysaccharides and carbohydrates contents estimation of mycelial extract of <em>S. commune</em> under submerged condition. Methanolic extracts of identified <em>S. commune</em> showed highest FRS (92.59%), chelating effect on ferrous ion (79.36%), reducing power (1.844) activities at 16, 1.5, 16 mg/ml concentrations respectively (<em>p</em>&lt;0.05). <em>S. commune </em>showed potent antibacterial activities (<em>p</em>&lt;0.05) against four bacterial strains except against <em>P. aeruginosa </em>where no activity was observed. The maximum inhibition zone was exhibited against <em>S. aureus</em> (20.2 mm) and minimum inhibition was found against <em>B. subtilis</em> (5.0 mm). This study recorded the highest dry weight (9.33 g/L) and rate of average growth (1.33 g/L/day) of <em>S. commune </em>in glucose (<em>p</em>&lt;0.05) medium but highest EPS (4.10 g/L) production was observed in xylose medium. Out of seven nitrogen sources, maximum mycelial yield (2.7 g/L), rate of average growth (0.38 g/L) and EPS (4.26 g/L) were recorded in yeast extract medium (<em>p</em>&lt;0.05). In glucose (0.597 g/100g) and yeast extract (0.006 g/100g) medias, the maximum amount of total carbohydrate was obtained from the EPSs of <em>S. commune</em>. That’s why it may be an excellent source of human medicines.</p> ER -