AFLATOXIN M1 INDUCING GENOTOXICITY AND PATHOLOGICAL LESIONS IN ORGAN MEATS, LIVER OF CATTLE SAMPLED FROM EL-BASATIN ABATTOIR, EGYPT
Keywords:Aflatoxins, liver, TLC, LC MS/MS, Comet, Cattle, Histopathology
In this study, two hundred and thirteen liver samples were randomly collected from different ages and both sexes of cattle carcasses in El-Basatin abattoir, Cairo governorate, Egypt. One hundred ninety- seven samples out of the examined specimens were free from any bacterial infections; but showed enlargement and pallor. Thirty-nine specimens representing about 20% of the bacteria- free specimens were examined to detect the Aflatoxins and its metabolites using thin layer chromatography (TLC) and LC MS/MS. All Pathological appraisals were recorded and the genotoxicity of the studied mycotoxin was detected using single cell gel electrophoresis (Comet). Our study revealed that there were prominent deleterious effects of Aflatoxin M1 on the hepatic tissue. The detection of aflatoxinsâ€™ metabolites in the hepatic tissues is of great importance on the health of human consuming organ meat; and on the other hand, it may affect the farm animalsâ€™ performance.
How to Cite
Copyright (c) 2021 Islam El- Gohary, Reham Abd-Elsalam, Nasser Fadal, Mahmoud Mahmoud
This work is licensed under a Creative Commons Attribution 4.0 International License.
All papers published in the Journal of Microbiology, Biotechnology and Food Sciences are published under a CC-BY licence (CC-BY 4.0). Published materials can be shared (copy and redistribute the material in any medium or format) and adapted (remix, transform, and build upon the material for any purpose, even commercially) with specifying the author(s).