ANTIFUNGAL AND CYTOTOXIC ACTIVITIES OF FIVE TRADITIONALLY USED INDIAN MEDICINAL PLANTS

Authors

  • Adhikarimayum Haripyaree
  • Kshetrimayum Guneshwor
  • Maibam Damayanti

Keywords:

Antimicrobial activity, minimum inhibitory concentration (MIC), agar well diffusion method, range test

Abstract

Hexane, Methanol and Distilled water extracts of five Indian Medicinal plants viz., Mimosa pudica L, Vitex trifolia Linn, Leucas aspera Spreng, Centella asiatica (L) Urban and Plantago major Linn belonging to different families were subjected to preliminary antimicrobial screening against six standard organisms viz., Ceratocystis paradoxa, Aspergillus niger, Penicillium citrinum, Macrophomina phaseoli, Trichoderma viride and Rhizopus nigricans. To evaluate antifungal activity agar well diffusion method was used. In addition LD50 of the same plant extracts were determined by using Range test on Mus musculus for cytotoxic activity. Methanolic extract of M. pudica showed the highest and significant inhibitory effect against some fungal species. Again, methanolic extract of M. pudica displayed the greatest cytotoxic activity.

Downloads

Download data is not yet available.

Downloads

Published

2013-02-01

How to Cite

Haripyaree, A., Guneshwor, K., & Damayanti, M. (2013). ANTIFUNGAL AND CYTOTOXIC ACTIVITIES OF FIVE TRADITIONALLY USED INDIAN MEDICINAL PLANTS. Journal of Microbiology, Biotechnology and Food Sciences, 2(4), 2272–2278. Retrieved from https://office2.jmbfs.org/index.php/JMBFS/article/view/7491

Issue

Section

Microbiology