EFFECT OF LIFETIME LOW DOSE EXPOSURE TO CADMIUM ON LIPID METABOLISM OF WISTAR RATS

Authors

  • Viera Almášiová
  • AgneÅ¡a Lukačínová
  • Katarína Holovská
  • Viera Cigánková
  • FrantiÅ¡ek NiÅ¡tiar

Keywords:

cadmium, lipid metabolism, rats, toxicology

Abstract

The aim of the study was to assess the effects of exposure to low doses of cadmium dissolved in drinking water (at a concentration 200 times higher than the maximum permissible dose) on lipid metabolism in 20 Wistar rats. Animals were divided into two groups, control and experimental. Experimental animals were exposed to low doses
of cadmium chloride in concentration of 20 μM of drinking water. The biochemical parameters determined in blood plasma included lipase, triglyceride, cholesterol and HDL-cholesterol in blood of rats. Lipase decreased; triglycerides, cholesterol and HDL-cholesterol were not changed in rats exposed to cadmium. The objective assessment of potential damage should consider not only the final results but also levels of the investigated parameters throughout the trial, i.e. in its individual stages.

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Published

2012-08-01

How to Cite

Almášiová, V., Lukačínová, A., Holovská, K., Cigánková, V., & NiÅ¡tiar, F. (2012). EFFECT OF LIFETIME LOW DOSE EXPOSURE TO CADMIUM ON LIPID METABOLISM OF WISTAR RATS. Journal of Microbiology, Biotechnology and Food Sciences, 2(1), 293–303. Retrieved from https://office2.jmbfs.org/index.php/JMBFS/article/view/7207

Issue

Vol. 2 No. 1 (2012): August - September

Section

Biotechnology

License

Copyright (c) 2012 Viera Almášiová, AgneÅ¡a Lukačínová, Katarína Holovská, Viera Cigánková, FrantiÅ¡ek Ništiar

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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