A REVIEW ON PROTEIN PRODUCTION AND SECRETION IN EUKARYOYTES

NANDINI B NATARAJ; Raja Sudhakaran

doi:10.55251/jmbfs.10555

A REVIEW ON PROTEIN PRODUCTION AND SECRETION IN EUKARYOYTES

Authors

NANDINI B NATARAJ Vellore Institute of Technology; Anthem Biosciences Pvt Ltd https://orcid.org/0000-0001-8301-6398
Sudhakaran R School of BioSciences and Technology, Vellore Institute of Technology, Vellore - 632014, Tamil Nadu

DOI:

https://doi.org/10.55251/jmbfs.10555

Keywords:

E. coli: Escherichia coli, protein translocation, glycosylation, protein folding, vesicular sorting

Abstract

Protein secretion is an important process in any living organism, and this is mediated by numerous steps and several cellular components. This review provides an overview of protein production from nascent polypeptide synthesis stage to secretion of these proteins into extracellular space by vesicular sorting. This review also provides insights on the factors involved in ER and Golgi in this pathway and their role. It also covers responsibility of translocons and chaperones in stress response pathways such as UPR and ERAD. Beyond all these a series of quality control checks are performed by cellular machinery to ensure the quality of protein delivered. So essentially this review covers all the pathways involved from initiation of protein expression to secretion.

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Published

2024-04-25

How to Cite

B NATARAJ, N., & Sudhakaran, R. (2024). A REVIEW ON PROTEIN PRODUCTION AND SECRETION IN EUKARYOYTES. Journal of Microbiology, Biotechnology and Food Sciences. https://doi.org/10.55251/jmbfs.10555

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Issue

Articles in press

Section

Biotechnology

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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