ANTIADHESIVE EFFECTS OF EXOPOLYSACCHARIDES ISOLATED FROM LIMOSILACTOBACILLUS REUTERI

Monika Holécyová; Juraj Pistl; Radomíra Nemcová; Eva Styková; Marián Maďar; Pavol Fedor; Marián Prokesš

doi:10.55251/jmbfs.11574

ANTIADHESIVE EFFECTS OF EXOPOLYSACCHARIDES ISOLATED FROM LIMOSILACTOBACILLUS REUTERI

Authors

Monika Holécyová Department of Pharmacy and Social Pharmacy, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovakia https://orcid.org/0000-0003-0184-155X
Juraj Pistl Department of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovakia
Radomíra Nemcová Department of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovakia https://orcid.org/0000-0002-3244-4058
Eva Styková Clinic of Horses, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovakia https://orcid.org/0000-0001-8659-1670
Marián Maďar Department of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovakia https://orcid.org/0000-0001-9347-2987
Pavol Fedor Children's hospital Košice, Košice, Slovakia https://orcid.org/0000-0003-4745-3552
Marián Prokesš University of Veterinary Medicine and Pharmacy in Košice https://orcid.org/0000-0002-3663-8765

DOI:

https://doi.org/10.55251/jmbfs.11574

Keywords:

Lactobacillus reuteri, Staphylococcus aureus, Proteus mirabilis, lactic acid bacteria, exopolysaccharide, antiadhesive effect

Abstract

Probiotics with their biological properties and products contribute to optimal functioning of organ systems and form a natural barrier against the growth of undesirable microorganisms. Exopolysaccharides (EPS) isolated from selected strains of Lactobacilli are tested for their antiadhesive, anti-biofilm and other beneficial effects. EPS isolated from the SL16 strain of Limosilactobacillus reuteri (formerly Lactobacillus reuteri) significantly reduced adhesion of Staphylococcus aureus CCM 3953 and Proteus mirabilis CCM 7188, and this effect was directly proportional to EPS concentration and stronger against S. aureus CCM 3953. Achieved results indicated an anti-biofilm potential of EPS obtained from intestinal Lactobacilli, probably attributable to antiadhesive activity of the tested EPS. Further studies will be required in order to clarify a mechanism of the anti-biofilm effect at the molecular level. Within the research into innovative anti-biofilm agents (biodegradable and non-toxic), the results obtained may facilitate the development of more efficient procedures or preparations that will be used in pharmacotherapy.

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Published

2025-05-22

How to Cite

Holécyová, M., Pistl, J., Nemcová, R., Styková, E., Maďar, M., Fedor, P., & Prokesš, M. (2025). ANTIADHESIVE EFFECTS OF EXOPOLYSACCHARIDES ISOLATED FROM LIMOSILACTOBACILLUS REUTERI. Journal of Microbiology, Biotechnology and Food Sciences, 15(1), e11574. https://doi.org/10.55251/jmbfs.11574

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Issue

Vol. 15 No. 1 (2025): August - September

Section

Microbiology

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